Chargers vs. Lions 2025 Hall of Fame Clash: Who’s Poised to Shock the Football World?

Chargers vs. Lions 2025 Hall of Fame Clash: Who’s Poised to Shock the Football World?

The total for Chargers-Lions at DraftKings is 33.5 (Over -115, Under -105). Detroit is a -1.5 favorite (-110) and -135 on the moneyline. Los Angeles is getting +1.5 (-110) and a +114 moneyline underdog. Because only backups and players just trying to earn a roster spot are suiting up Thursday, there are no player props listed at the time of writing. 

Regardless, a wise man once said, “Beggars can’t be choosers,” so at least we have football to watch and bet on. 

Detroit’s “brain drain” is the biggest factor in this game. Former Lions defensive coordinator Aaron Glenn was hired by the New York Jets to be their head coach this offseason, and former offensive coordinator Ben Johnson took the Chicago Bears’ head coaching gig. Glenn was Campbell’s DC for the last four seasons, and Johnson has been Detroit’s OC for the past three years.

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