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Clarendon's Shocking Picks for March Madness 2025: Upsets Guaranteed

Clarendon's Shocking Picks for March Madness 2025: Upsets Guaranteed

As March rolls around, the air is charged with anticipation—March Madness is upon us, and the buzz is inescapable. Who will we root for? Who will make us jump off our seats with excitement or, indeed, heartbreak? But beyond the brackets, statistics, and player performances, there’s a story, a personal odyssey for many like myself, who’ve played their heart out in those very games. Here I am again, drawn back into the fray, with an amalgam of nostalgia and the thrill of new narratives. Can grand dame Dawn Staley take South Carolina to new heights this year after becoming the top seed? Or will Iowa make significant noise sans Clark and Martin? These are not mere games; they’re moments of pure, unadulterated competitive spirit that take us all on a rollercoaster of emotions. From my own experience, from the camaraderie of huddling with teammates on Selection Sunday, waiting to see if you’ve made the cut… It's a journey I know all too well. And now, with the abundance of talent, like Juju Watkins or the sensational Paige Bueckers, and even some unexpected underdogs set to steal the show, we stand at the precipice of something monumental but who, in this game of constant surprises, will actually take the plunge? LEARN MORE by checking out my article where I dive into the possibilities, the probabilities, and shed some light on those emotional March dance stories, sharing my absolutely biased opinions based on the data provided by our esteemed friends at Opta. LEARN MORE

Former Cal star and WNBA All-Star Layshia Clarendon breaks down the 2025 Women’s NCAA Tournament and shares which teams are poised for a deep run.


It’s that time of year. March, and the madness is electric.

I recall the joy of Selection Sunday my senior year, holding hands with my teammates, staring up at the screen waiting to hear our name called. We screamed as the California Golden Bears were revealed as the No. 2 seed, the highest in school history. Our gritty, fun loving, eclectic group danced all the way to the 2013 Final Four.

One of my proudest sports accomplishments. 

March is about joy, living in the moment, and, most importantly, intense college basketball competition. It doesn’t matter what you did up to that point. Win or go home isn’t just a fun sports saying. The pressure is paramount. Getting an opportunity to dance in March is what the college season is all about. The women’s game has grown tremendously over the last decade and has exploded in recent years with a variety of talent and storylines. 

  • Can Dawn Staley and the 2023-2024 national champion South Carolina Gamecocks repeat? 
  • What noise can Iowa make without Clark and Martin? 
  • Is Texas overrated? 
  • Is it Final Four or bust for USC? 
  • What underdogs will emerge and steal our hearts?

The star power will be on full display with the likes of Juju Watkins, Flau’jae Johnson, Hannah Hidalgo, Paige Bueckers, Kiki Iriafen, Lauren Betts, Madison Booker, MiLaysia Fulwiley, Ta’Niya Latson, Aziaha James, Kiki Rice and many more. 

There are so many things to consider, especially when you factor in the scoring of our Opta Analyst Predictor Bracket, which rewards you for nailing upset picks.

The scoring system is based on our supercomputer running simulations of the 2025 NCAA Tournament to determine how likely it is that a particular team will reach a particular round. If you pick a team that has a 70% chance of advancing past the first round and that team wins, you’ll receive 30 points (100% minus the percentage chance your selection will advance). If it has a 45% chance of advancing past the second round to the Sweet 16 and again advances, you’ll get 55 points. If it has a 20% chance of reaching the Elite Eight and you get that pick right, you’ll get 80 points. With that in mind, I’ve highlighted some upset picks that could get you plenty of points if they come through.

Selection Sunday should be a national holiday. We’ll get to working on that. In the meantime, here are my absolutely biased opinions. 

My 2 Cents: UCLA, fresh off a Big Ten conference tournament win over USC, is the heavy favorite. The combo of Kiki Rice and Lauren Betts anchors the Bruins. Betts finished in the top five in the Big Ten in scoring, rebounds and blocks per game. If we look ahead at the national championship game. UCLA versus South Carolina could be a buzz-worthy matchup in Tampa. 

NC State could make a deep run, but the big question for me is Aziah James’ health. She was getting buckets versus Duke in the ACC tournament and it seemed like NC State’s game to lose when she took a hard fall along the baseline. She returned in the second half, but the team could not recover.

NC State with a healthy version of her is lethal. Saniya Rivers boasts WNBA talent. Zoe Brooks is a consistent combo guard. NC State’s guard play is phenomenal, but the team is extremely young and vulnerable inside. NC State’s greatest asset is breaking people down 1-on-1, which can also be the team’s greatest weakness at times when ball movement is key. 

Dark Horse: Florida State. Ta’Niya Latson is a walking bucket and doesn’t get enough national attention. Combine that with what Makayla Timpson can do inside and that makes for a dangerous duo. I think the Seminoles have the toughness and just enough star power to take on LSU. 

First Round

No. 1 UCLA over No. 16 UC San Diego 
No. 9 Georgia Tech over No. 8 Richmond
No. 5 Ole Miss over No. 12 Ball State 
No. 4 Baylor over No. 13 Grand Canyon
No. 6 Florida State over No. 11 George Mason
No. 3 LSU over No. 14 San Diego State 
No. 10 Harvard over No. 7 Michigan State 
No. 2 NC State over No. 15 Vermont 

Second Round

No. 1 UCLA over No. 9 Georgia Tech
No. 5 Ole Miss over No. 4 Baylor 
No. 6 Florida State over No. 3 LSU
No. 2 NC State over No. 10 Harvard

Sweet 16

No. 1 UCLA over No. 5 Ole Miss
No. 2 NC State No. 2 6 Florida State

Elite Eight

No. 1 UCLA over No. 2 NC State

My Two Cents: USC vs. UConn in the Elite Eight seems like something that should be happening in the Final Four. It is the JuJu vs. Paige rematch. Back in December, USC came out on top and Juju won the head-to-head matchup against Paige. While JuJu finished with 25 points and Paige 22, Watkins’ overall stats were more impressive and efficient across the board. What I’m most excited to see with this potential matchup is how UConn game plans against the Trojans.

The top scorers in the Women's NCAA Tournament

Coach Geno Auriema and the Huskies, who won the Big East tourney, are hungry for revenge and a trip to the Final Four. USC failed to make it to the Final Four last season and is riding the wave of putting the Trojans back on the women’s basketball map as the historical powerhouse it is.

But here’s the plot twist; March is about our hearts. I’m a California Golden Bear, and USC has been a deep-seeded rival for years in the Pac-12. I’m going with my Bears, with one of the best 3-point shooting duo’s in the country, to take down USC on their home court. And picking Cal to win in the second round could give me 89 points compared to the 22 points I’d get for going chalk with USC. So the scoring rewards me following my heart.

Worst case, JuJu vs. Paige rematch. I’ll settle for that if needed. I’m calling Iowa over Oklahoma and looking forward to seeing Hannah Stuelke and Raegan Beers go at it. 

First Round

No. 1 USC over No. 16 UNC Greensboro
No. 8 California over No. 9 Mississippi State 
No. 5 Kansas State over No. 12 Fairfield
No. 4 Kentucky over No. 13 Liberty
No. 6 Iowa over No. 11 Murray State
No. 3 Oklahoma over No. 14 FGCU
No. 10 South Dakota State over No. 7 Oklahoma State
No. 2 UConn over No. 15 Arkansas State 

Second Round

No. 8 California over No. 1 USC (Please basketball Gods!)
No. 4 Kentucky over No. 5 Kansas State
No. 6 Iowa over No. 3 Oklahoma 
No. 2 UConn over No. 10 South Dakota State

Sweet 16

No. 4 Kentucky over No. 8 California
No. 2 UConn over No. 6 Iowa 

Elite Eight

No. 2 UConn over No. 4 Kentucky 

My Two Cents: South Carolina. Dawn Staley. That’s it. Perhaps the committee thought the previous national champions needed a bit of motivation in giving the Bruins the No. 1 overall seed. A chip on the Gamecocks’ shoulder, perhaps. March is March so nothing is promised, but it looks like South Carolina’s Final Four opportunity to lose. What Dawn has built from the ground up while delivering sustained success should absolutely be heralded. 

The probabilities of the top teams to win the championship in the Women's Tournament

I’m picking Vanderbilt as a sleeper to upset No. 2 Duke. Shae Ralph has led the team to back-to-back tournament appearances, she knows end of game situations well and they could make some noise. Duke, while solid defensively, has struggled at times to consistently knock down open shots. The Blue Devils are led by one of the great basketball minds in Kara Lawson. I want this game to come down to a nailbiter of timeouts, great drawn-up plays, but ultimately players on the court being the deciding factor. When you factor in Vandy potentially getting me 62 points with a win over Duke in the Predictor Bracket, I think it’s worth taking a shot on the Commodores.

Also, North Carolina could give South Carolina a run for its money. The Tar Heels have solid guard play with Reniya Kelly’s midrange game, Lexi Donarski’s 3-point shooting, and overall toughness with Alyssa Ustby. They’re also extremely well coached by Courtney Banghart. 

First Round

No. 1 South Carolina over No. 16 Tennessee Tech
No. 9 Indiana over No. 8 Utah
No. 5 Alabama over No. 12 Green Bay
No. 4 Maryland over No. 13 Norfolk State
No. 6 West Virginia over No. 11 Washington
No. 3 North Carolina over No. 14 Oregon State 
No. 7 Vanderbilt over No. 10 Oregon 
No. 2 Duke over No. 15 Lehigh

Second Round

No. 1 South Carolina over No. 9 Indiana 
No. 5 Alabama over No. 4 Maryland 
No. 3 North Carolina over No. 6 West Virginia 
No. 7 Vanderbilt over No. 2 Duke 

Sweet 16

No. 1 South Carolina over No. 5 Alabama 
No. 3 North Carolina over No. 7 Vanderbilt

Elite Eight

No. 1 South Carolina over No. 3 UNC

My Two Cents: TCU has had an awesome year, and with Madison Conner, Hailey Van Lith and Sedona Prince, they’re boasting an impressive Big 3 right now. Prince is a large target down low but can also step outside, making her a unique weapon. I would love to see a Texas vs TCU matchup in the Elite Eight, but I don’t think it’s going to happen because of the Fighting Irish.

They did not finish the season on a high note, ending on a 3-2 record heading into Selection Sunday after being so dominant. Sometimes those losses are just what you need to remind you that rankings of the past don’t matter. You’ve got to show up every single night. Unfortunately, watching Texas play South Carolina gave me pause about them.

Is it fair to measure the Longhorns up against the defending champs? Absolutely. Because at some point, Texas can’t only hang its hat on defense. It will only take the Longhorns so far.

There are too many high-octane players and programs out there. You’ve got to score. Madison Booker cannot do it alone and the team’s offensive production is too unpredictable. Maybe the Longhorns actually have the biggest chip on their shoulder. I’m actually going to call it a three-way tie between Texas, Notre Dame and TCU. They all have a lot to prove under the bright lights of March. 

First Round

No. 1 Texas over No. 16 High Point
No. 8 Illinois over No. 9 Creighton
No. 5 Tennessee over No. 12 South Florida
No. 4 Ohio State over No 13 Montana State
No. 6 Michigan over No. 11 Princeton
No. 3 Notre Dame over No. 14 SF Austin
No. 7 Louisville over No. 10 Nebraska 
No. 2 TCU over No. 15 FDU

Second Round

No. 1 Texas over No. 8 Illinois
No. 5 Tennessee over No. 4 Ohio State 
No. 3 Notre Dame over No. 6 Michigan
No. 2 TCU over No. 7 Louisville 

Sweet 16

No. 1 Texas over No. 5 Tennessee
No. 3 Notre Dame over No. 2 TCU

Elite Eight

No. 3 Notre Dame over No. 1 Texas 

Layshia Clarendon's Final Four Picks

No. 1 UCLA over No. 2 UConn 
No. 1 South Carolina over No. 3 Notre Dame 

No. 1 UCLA over No. 1 South Carolina 


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The post March Madness 2025: Layshia Clarendon’s Expert Women’s NCAA Tournament Picks appeared first on Opta Analyst.

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