
USC’s 2025 Season: Shocking Game-by-Game Predictions That Could Change Everything
Pick: USC 48 – Missouri State 7 (1-0)
Week 2- Georgia Southern
Georgia Southern coming to town means the return of Clay Helton to USC. Clay Helton coached at USC from 2010 through 2021, spending 2015-2021 as the head coach. He was fired just two games into the 2021 season, and surely would like revenge on his old school. They do bring back two of their top offensive pieces from last year, with JC French back at quarterback and running back OJ Arnold returning as well. Still, this was a defense that was 83rd in opponent points per game and 114th in opponent yards per game. They have not improved enough on that side of the ball to compete here.
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