Week 15 NFL Showdowns: Uncover the Surprising Picks and Hidden Odds That Could Shake Up the Season
Tennessee Titans (2-11) at San Francisco 49ers (9-4)
- Opta Supercomputer’s Win Probability: 49ers 56.6%
- DraftKings Point Spread: 49ers -12.5
- All-Time Regular Season Meetings: 49ers 9-6
- Last Meeting: Titans 20, 49ers 17 (Dec. 23, 2021)
Quick Hit: The Titans and 49ers have alternated wins in each of the past five matchups in San Francisco, with all five games decided by seven or fewer points. Tennessee interim coach Mike McCoy won his only game in San Francisco back when he was head coach of the Chargers in Week 16, 2014 (won 38-35).
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