LSU vs. Clemson Week 1 Clash: Uncover the Shocking Underdog Pick and Must-Know Odds!
It is Week 1 of the college football season, as LSU football hosts Clemson football. This will be the debut of Lane Kiffin as the head coach of the Tigers. It is time to continue the NCAA Football odds series with a Clemson-LSU prediction and pick.
Clemson comes into the season unranked in the preseason AP Poll, making it the first time since 2011 that they did not enter the season ranked. They were the top team receiving votes, while also being ranked 23rd in the coaches poll. Now, Clemson is looking for a bounce-back. In 2025, Clemson got off to a slow start. After losing their opening game to LSU, they would defeat Troy before dropping games to Georgia Tech and Syracuse. Still, the Tigers would win six of their last eight games, including the final four games of the regular season to make a bowl game. In the Pinstripe Bowl against Penn State, Clemson lost 22-10.
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